Events

Peng Ji, MD, PhD
Northwestern University Feinberg School of Medicine

Title: "Bone marrow inflammation in the pathogenesis of myeloid neoplasm"

Description: In his talk, Dr. Ji will describe the significance of inflammation of the bone marrow microenvironment in the pathogenesis of myeloid neoplasms, particularly in clonal hematopoiesis and myelodysplastic syndromes. The focus will be on how gasdermin D-mediated pyroptotic signaling induces a vicious cycle of mutant myeloid clones and adaptive immune responses in driving myeloid neoplasms. 

Host:
Shan Zha, MD, PhD
James A Wolff Professor of Pediatrics, Pathology and Cell Biology and of Microbiology and Immunology (in the Institute for Cancer Genetics and in the Herbert Irving Comprehensive Cancer Center)